Radiology and Physical Medicine

Critiquing Scientific Papers

BYSTANDER EFFECTS AND RADIOTHERAPY EFECTOS BYSTANDER Y RADIOTERAPIA

September 9, 2015 | Translate

Firstly, this is a topic of interest to the electronic platform in which it is published (Sciencedirect)1, because this platform deals with, among other things, current medical issues. The topic has a great medical interest because bystander effects, radiotherapy and other issues are better known and can be investigated more easily due to the increasingly […]

Para comenzar, el tema tratado es de interés para la plataforma electrónica en la que se publica (Sciencedirect)1, puesto que dicha plataforma trata, entre otras cosas, de temas de actualidad médica. El tema tratado es de gran interés médico ya que los efectos bystander, la radioterapia y [...]

THE ROLE OF TELOMERES IN PREDICTING INDIVIDUAL RADIOSENSITIVITY OF PATIENTS WITH CANCER IN THE ERA OF PERSONALIZED RADIOTHERAPY THE ROLE OF TELOMERES IN PREDICTING INDIVIDUAL RADIOSENSITIVITY OF PATIENTS WITH CANCER IN THE ERA OF PERSONALIZED RADIOTHERAPY

September 9, 2015 | Translate

This is a review of several articles where it speaks of the enormous importance of human telomeres from the point of view of the radiosensitivity. It is a review published in the journal called Cancer Treatment Reviews1, and its content is entirely appropriate to the subject of this magazine2. The title tells […]

Se trata de una revisión de varios artículos en la que se habla de la enorme importancia que tienen los telómeros humanos desde el punto de vista de la radiosensibilidad. Está publicada en la revista Cancer Treatment Reviews1, y su contenido es totalmente apropiado al tema de esta [...]

TARGETING A CORNERSTONE OF RADIATION RESISTANCE: CANCER STEM CELL TARGETING A CORNERSTONE OF RADIATION RESISTANCE: CANCER STEM CELL

September 9, 2015 | Translate

We are facing an integrated narrative minireview. As its abstract introduce, this minireview compiles the latest research on the pathophysiological mechanisms of cancer stem cells (CSCs), it explain their radioresistance, which could give explanation for their capacity to cause tumor recurrence. Furthermore the review will introduce news therapeutics orientations against CSCs. Therefore, it shows a […]

Nos encontramos ante una mini revisión narrativa integradora. Como nos explica el resumen, recopila las últimas investigaciones sobre los mecanismos patofisiológicos de las células madres tumorales (Cancer stem cells, CSCs), a los que debe su capacidad de radioresistencia y posible explicación de la capacidad de recurrencia tumoral. A [...]

MICRORNA IN RADIOTHERAPY: MIRage OR MIRador? MICRORNA IN RADIOTHERAPY: MIRage OR MIRador?

September 9, 2015 | Translate

The article is published in the British Journal of Cancer (2015). Its title, “MicroRNA in radiotherapy: miRage or miRador?” could lead to error because it does not specify clearly enough the content. Firstly, because it doesn’t appear in any part of the article so it is not clear what is meant by this; and secondly, […]

Este artículo está publicado en el British Journal of Cancer (2015). Su título puede llevar a confusión ya que no explica claramente el contenido. En primer lugar, en ninguna parte del artículo aparece explicado el significado de “miRage” o “miRador” por lo que no está claro qué quiere [...]

INHIBITION OF BOTH EGFR AND IGF1R SENSITIZED PROSTATE CANCER CELLS TO RADIATION BY SYNERGISTIC SUPPRESSION OF DNA HOMOLOGOUS RECOMBINATION REPAIR INHIBITION OF BOTH EGFR AND IGF1R SENSITIZED PROSTATE CANCER CELLS TO RADIATION BY SYNERGISTIC SUPPRESSION OF DNA HOMOLOGOUS RECOMBINATION REPAIR

September 8, 2015 | Translate

The theme of the article is within the disciplines that may be included in this magazine: PLOS ONE (initially PLoS ONE, PLOS ONE from 2012) which is a scientific journal published by the Public Library of Science (PLOS). It is an open access publication, the corresponding license is Creative Commons Attribution 2.5 Generic. Mainly integrates […]

El tema del artículo está dentro de las disciplinas que pueden incluirse en esta revista: PLOS ONE (inicialmente PLoS ONE, PLOS ONE a partir del 2012) la cual es una revista científica publicada por Public Library of Science (PLOS). Se trata de una publicación de acceso libre, la licencia correspondiente es Creative Commons Attribution 2.5 Generic. Integra principalmente [...]

Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis

August 14, 2014 | Translate

The selected journal for the publication of the review is “Mutation Research-Reviews” whose subject area is the investigation of mutations and their applications, particularly focusing on the relationship between mutations and disease. So, the review is related with the subject area of the journal. The impact factor is 6.426 and the impact factor for five […]

La revista escogida para la publicación de la revisión es "Mutation Research-Reviews", cuya área temática es la investigación de las mutaciones y sus aplicaciones, especialmente centrada en la relación entre las mutaciones y la enfermedad. Por tanto, la revisión está relacionada con el área temática de dicha revista. El factor [...]

Targeting DNA double-strand break signalling and repair: recent advances in cancer therapy Targeting DNA double-strand break signalling and repair: recent advances in cancer therapy

August 14, 2014 | Translate

In this article we will make reference to the lesions at a DNA level (DSB), as well as the way they act against them and the relationship between them. The relation to the therapeutic field with radiotherapy or chemostherapy, all of which has been tested through trials and studies, most of which have been carried […]

En este artículo haremos referencia a las lesiones a nivel del ADN (RDC) , así como su actuación ante ellas y su relación en el ámbito terapéutico con la radioterapia y quimioterapia, todo ello argumentado a través de ensayos y estudios la mayoría de ellos recientes.

Oxidative Stress and Skin Cancer: An Overview Oxidative Stress and Skin Cancer: An Overview

August 14, 2014 | Translate

The theme of this article is, at first, right for the journal it is published in because it deals with biochemical processes. However, its applications would be more useful in clinical fields, so it would have been better to publish it in a medical related journal. The title is not correct at […]

El objeto de este artículo es, en principio, correcto para la revista en que se publica, pues habla de un tema de interés desde el punto de vista bioquímico. Si bien, sus aplicaciones estarían más orientadas a un nivel clínico, por lo que podría haber sido publicada en una revista [...]

The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved? The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?

August 13, 2014 | Translate

The article is published in the “International Journal of Radiation Oncology” (impact factor: 4.524). Its title, “The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?” does not specify clearly enough the content. A proposal might be: “The tumor radiobiology of SRS and SBRT: it´s a new biological explicative model needed?” […]

El artículo está publicado en la revista “International Journal of Radiation Oncology” (factor de impacto: 4.524). Su título “Radiobiología tumoral del SRS y el SBRT: ¿hay más que las cinco R involucradas?” no especifica claramente el contenido del mismo, que a propuesta podría ser: “Radiobiología tumoral del SRS y el [...]

DNA reparation mechanisms as therapeutic target Mecanismos de reparación del ADN como diana terapéutica

August 12, 2014 | Translate

Chemotherapy and radiotherapy treatments are the main procedures currently used for cancer therapeutics. They are based on the production of lethal and sublethal damage on neoplastic cell’s DNA to cause his death. The results obtained in terms of survival with these therapies are increasing every day, but its curative potential its often limited by intrinsic […]

Los tratamientos con quimio y radioterapia son los principales procedimientos que se utilizan actualmente como terapéutica del cáncer. Se basan en la producción de daños letales y subletales sobre el ADN de la célula neoplásica para provocar su muerte. Los resultados obtenidos en cuanto a supervivencia con estas terapias son [...]